Thursday, November 27, 2014

Is a Divide Developing Within the LCHF Camp over the importance of using ketones for energy?

Dr. Michael Eades has argued that the Inuit used ketones as a key energy source on their traditional diet, that the only reason they weren't measured as producing many ketones is that they were "ketoadapted," and that using ketones was a good thing for them, and also a good thing for others to emulate:
"according to most of what I’ve read, the Inuit ate a diet made of about 50 percent caribou, 30 percent fish, 10 percent seal and 10 percent rabbit, polar bear, birds and eggs. These are the figures Stefansson quotes, but they are confirmed by others. Both Stefansson and Murdoch, who wrote the ethnology report for the government in the late 1800s (predating Stefansson) reported that the Inuit ate about the same amount of food, in terms of calories, as a standard American and ate the same amount of fat. I’m not sure I agree, but that’s what they reported. I would think they would have eaten more fat.

... I can tell you from many years of experience treating patients on low-carb diets that you don’t have to eat a 70-80% fat diet to go into ketosis. You can eat steak, chicken, lamb chops, virtually any kind of meat along with a salad and a green vegetable and get nicely into ketosis. And stay there for a good while. Ultimately, if you stick with such a diet, you end up ketoadapted and your level of measurable ketones fall.

He even argued against eating too much protein, so as to avoid slowing down the ketogenic process;
"keep an eye on the protein intake. Too much protein will prevent the shift into ketoses [sic] because the liver will convert some of the protein into glucose – this glucose will then be used first and slow down the ketogenic process.  Which, if course, prompts the question, how much protein is too much?  As long as you’re getting your protein from meat, especially fatty cuts of meat, you’re probably okay.  If you go for the extremely lean cuts of meat, say, skinless chicken breasts, or if you are supplementing your diet with low-fat protein shakes, you could have a little more trouble low-carb adapting."

Peter of the Hyperlipid/high-fat-nutrition blog recently hypothesized that most of the Inuit (and other Artic/subarctic peoples) "did not develop high levels of ketones," due to a genetic mutation:

The P479L gene for CPT-1a and fatty acid oxidation

Peter: "I have some level of discomfort with using the Inuit as poster people for a ketogenic diet. That's fine. They may well have eaten what would be a ketogenic diet for many of us, but they certainly did not develop high levels of ketones when they carried the P479L gene. ...

Ultimately, point scoring on the internet about what the Inuit did or didn't eat shouldn't destroy people's chances of health. Destroying a circular argument about Inuit diets may [make] the destructor feel good. ...."

Dr. Eades does not appear to agree with this hypothesis:

Michael R. Eades, M.D. said...
"@Tim Steele

You wrote: "I'm not sorry I helped topple a faulty core tenant of the modern day Ketogenic Diet."

Pretty hubristic, I would say. I would argue that it hasn't come close to being toppled by you or anyone else."

It will be interesting to see where this debate leads.

Sunday, August 24, 2014

Did You Know That There's Sugar in Your Shrimp and Lobster?

It was shocking enough for many in the Paleo/ancestral and LC communities to learn that there's a super-"safe" starch called resistant starch. When they get around to investigating trehalose, their minds may really be blown! Trehalose (aka "mushroom sugar") is a super-healthy sugar that's found in fungi (such as shiitake, maitake, nameko, and Judas's ear mushrooms), sea algae, honey, and even crustaceans (such as shrimp and lobster) and insects.

As with resistant starch, Paul Jaminet, the "safe-starches" guy, was ahead of the crowd, touching on trehalose back in 2010:

Trehalose may provide some amazing benefits. Physician and anti-aging researcher James Watson reported that trehalose "activates autophagy via an mTOR-independent mechanism." (Autophagy – the housekeeper in every cell that fights aging, Posted on 19 April 2013)

Paleo dieters and Peatarians alike might be interested to learn that trehalose has been found to suppress lipid oxidation, a partiular concern with polyunsaturated fatty acids (PUFAs) that are sensitive to oxidation. Trehalose may also "have a kind of suppressive effect on the development of osteoporosis." (Novel functions and applications of trehalose, Takanobu Higashiyama, Pure Appl. Chem., Vol. 74, No. 7, pp. 1263–1269, 2002.

Diabetics have been reporting that trehalose improves their blood sugar numbers. (JC Spencer, "The Sugar Trehalose is helping Diabetics,"

Trehalose even reduced the symptoms of parkinsonism in mice. (Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation, Neurobiol Dis., 2010,

Out of curiosity, I've been experimenting with a trehalose powder (I know, I know, an "evil processed powder"! ;-) ). Instead of causing my teeth and gums to become coated in gunk, I find it slightly cleans them. It seems to reduce my remaining minor dandruff a bit too, though that's more difficult to tell. I haven't noticed any negative effects. It's a bit pricey, though, so I doubt I'll buy much more of it. Trehalose may at least be another reason to eat mushrooms, crustaceans and honey, and some day maybe even insects.

Sunday, February 02, 2014

WARNING: Serious problems have been reported with very low carb diets

See Spanish Caravan's online comments about this, such as at

Resistant starch seems to be especially important. I recommend reading up on it and the Old Friends Hypothesis.